Neurobiology of Migraine: Genetics

Genetics Population-based epidemiological surveys and twin studies greatly support the idea that MO is produced by genetic and environmental influences (Goadsby, 2013). Epidemiological evidence demonstrates methyltetrahydrofolate reductase C677T gene mutation is...

Types of Migraine

Types of Migraine MO is a recurrent headache with several attacks occurring between 4 and 72 hours that is worsened by and/or causing avoidance of everyday physical activity (“The International Classification of Headache Disorders, 3rd edition (beta...

Clinical Trials

Clinical Trials Although clinical trials  are a substantial and rapidly growing international business, they are not well understood by the general public. They are often seen as obscure and are sometimes surrounded by controversy about the ethical aspects that touch...

Health Informatics

Health Informatics Health informatics is a developing field that is becoming progressively important to the quality and effective distribution of healthcare. Now any modern health organization can’t function efficiently without an electronic database storing,...

Image enhancement for low-vision patients

Based on the statistics of the World Health Organization (WHO), the population of  low-vision patients has reached around one hundred and sixty-five millions. Meanwhile, that population is still rising by twenty one millions per year . The prevalence rates of...

the Testing of Lower Extremity Medical Devices

Ankle-Foot Anatomy The ankle-foot complex has two important functions in walking: stable the stance, and provide propulsion. Therefore, an understanding of the anatomy of this area is essential for designing lower extremity medical devices. The ankle joint is the...

the Upper Extremity Rehabilitation Devices

Hand Anatomy The hand is responsible for nearly 90% of upper limb function. A large number of joints and bones provide the motion capabilities of the hand[8]. The hand has 27 bones, and the fingers are labeled digits 1-5, with the thumb as digit 1, and the little...

practical way to monitor smoking and environmental factors

practical way to monitor smoking and environmental factors Cigarette smoking is the principal cause of premature death and disability in the United States. Tobacco smoking is causally linked to 13 different types of neoplastic disease. Of the 230,000 Americans who are...

Matching of Micro-CT image With Histology

Matching of Micro-CT image With Histology Image registration is an emerging field in medical research which is concerned with aligning volumetric data from multiple modalities,  such as MRI, CT, ultrasound, and even histology. While registration algorithms for the...

Micro-CT Scanning

Micro-CT Scanning Micro-CT scanners use many of the same physical principles as traditional CT-scanners, but are engineered to accommodate smaller  samples. Beginning at x-ray production, the x-ray vacuum tube contains a tungsten filament through which a user inputted...

Micro-CT in Breast Cancer and Margin Assessment

Micro-CT in Breast Cancer and Margin Assessment Micro-CT scans of lumpectomy specimens are another proposed solution to intraoperative margin assessment. Micro-CT is a technology which allows for 3-dimensional imaging of smaller specimens, providing faster imaging...

Intraoperative techniques for determining margin status

Intraoperative techniques for determining margin status A concerted effort to reduce re-excision rates has produced an active interest in intraoperative margin status determination. A fast, accurate intraoperative method would allow surgeons to resect tissue while the...

Margin Status in Breast Conservation Therapy

Margin Status in Breast Conservation Therapy Margin status is a prevalent issue in cancer surgery, and especially so in lumpectomy procedures. Margin status refers to the presence of cancer on the surface of excised tissue, and is most often described in one of three...

Breast Cancer Treatment

Overview of Breast Cancer Treatment Breast Cancer is a serious issue in women’s health. It is the most prevalent invasive cancer in women with over 200,000 new cases in the US in 2013, and is the second leading cause of cancer death in women (“Cancer Facts &...

Medical Imaging Overutilization

Medical Imaging Overutilization Overutilization of medical imaging services is a healthcare disparity that may not be widely recognized by the healthcare industry, but this issue has known implications on quality, value, and safety of healthcare delivery....

Computer-aided diagnosis CAD

Computer-aided diagnosis (CAD) has become a vital part of medical evaluations and pathology detection in the United States [1]. Systematic use of CAD systems since 1980s has caused a signi ficant change in the utilization of the computer output for...

Texture Features in Cellprofiler

Haralick features Haralick features provide information on how the intensities of pixels in images of a certain position are related with the intensities of neighboring pixels. These features originated from the co-occurrence matrix. In the Cellprofiler  used...

Cellprofiler

CellProfiler is free open-source software or framework which enables pathologists and biologists who do not have specific knowledge in fields like computer vision, image processing and programming for quantitative measurement and evaluation of  the phenotypes from...

Lung Cancer

Lung cancer is the type of cancer in which there is unchecked growth of unusual cells either in one or in both the lungs. These anomalous cells do not perform the functions of healthy human cells and do not mature into normal cells. This abnormality affects the proper...

Cancer

Cancer is known as gathering of related illnesses. In a wide range of cancer, some portion of the body’s cells, start to separate without halting and spread into encompassing tissues. Human body is made up of cells which are trillions in number. Tumor can begin any...